In 1 Cor. 2:6-9 Paul says that the ‘the rulers of this age’ are being destroyed.
This can't refer to Rome and Jewish authorities who were at the height of their power.
Paul says that if these rulers had known that eternal life would be the effect of his death, they would not have killed him.
Thus rulers can't refer to humans.
Humans would want eternal life.
However the word ruler also refers to demons.
For example Ephesians 2.2.